Blockade of the ADAM8-Fra-1 complex attenuates neuroinflammation by suppressing the Map3k4/MAPKs axis after spinal cord injury

Abstract Background Mechanical spinal cord injury (SCI) is a deteriorative neurological disorder, causing secondary neuroinflammation and neuropathy.ADAM8 is thought to be an extracellular metalloproteinase, which regulates proteolysis and cell adherence, but whether its intracellular region is involved in regulating neuroinflammation in microglia

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Prospective study to assess the treatment modalities and fever defervescence in patients with scrub typhus from a tertiary care centre in South India

Background and objectives: Fever defervescence in scrub typhus, a zoonotic bacterial infection is used as a surrogate marker of disease resolution.Failure of fever defervescence prompts clinicians to suspect alternate diagnoses and treatment.In this observational study, various treatment regimens were correlated with clinical outcomes.Methods: All

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Domotics Project Housing Block

This document develops the study of an implementation project of a home automation system in a housing placed in the town of Galapagar, Madrid.This house, which is going to be occupied by a four-member family, consists of 67 constructed square meters distributed in lounge, kitchen, LEGO Minions three bedrooms, bath, bathroom and terrace, this being

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